Damiana has long been recognized to have a stimulating effect on libido, and its use as an aphrodisiac continues into modern times. Corroborating scientific evidence in support of its long history of use has also emerged recently.

Several animal studies have shown evidence of increased sexual activity in sexually exhausted or impotent male rats when exposed to damiana, as well as generally increased sexual activity in rats of both sexes. It has also been shown that damiana may function as an aromatase inhibitor, which has been suggested as a possible method of action for its reputed effects.

Damiana is an ingredient in a traditional Mexican liqueur which is sometimes used in lieu of Triple Sec in margaritas. Mexican folklore claims that it was used in the original margarita. The damiana margarita is popular in certain areas of Mexico.

Today damiana is used for enhancing male sexual capacity, respiratory diseases, asthma, depression, digestive problems, impotence, difficulty in achieving orgasm in women and menstrual disorders. Damiana appears to have a calming effect on the central nervous system. The herb damiana has been used in Mexico for some time as a male aphrodisiac. Classic herbal literature of the nineteenth century describes it as a tonic, or general body strengthener.

It appears on the FDA's GRAS (generally recognized as safe) list and is widely used as a food flavoring.

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